What is QTc Prolongation and How to Manage a Prolonged QTc interval in Psychiatry? - Sanil Rege

In this video Dr Sanil Rege discusses QTc prolongation, the effect of antipsychotics and antidepressants on QTc, risk factors for QTc prolongation and how best a physician can manage prolonged QTc interval.
There are currently no clear guidelines with regards to prescribing, and monitoring of psychotropic medications in the context of QTc and this video is meant to provide some guidance with regards to the use of psychotropic medications and QTc interval prolongation.

Psychotropic drugs are known to be associated with a prolonged QTc interval with differing risk profiles which will be discussed in this video. As psychotropic drugs prolong cardiac repolarization, they increase the risk of Torsades de Pointes (TdP).

Both typical and atypical psychotic medications have been associated with QTc interval prolongation and sudden cardiac death.

Clinicians should be aware of the varied risk profiles of psychotropics concerning the QTc interval and take into account the various static and dynamic risk factors. A risk-benefit analysis should be carried out when prescribing medications that prolong QTc.

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